Buprenorphine Overview

What is Buprenorphine?

In 2002, buprenorphine was approved by the FDA to be used in the treatment of narcotic dependence in adults. Also referred to by its brand name, Subutex, this drug is used in the beginning stages of treatment to prevent the patient from experiencing harsh withdrawal symptoms from opioid-based medications and street drugs. Buprenorphine is derived from thebaine, which is extracted from opium and should only be administered as a part of a complete opioid addiction treatment plan.

How is Buprenorphine Administered?

You must use buprenorphine exactly as directed to receive the full benefits of this medication. This drug is sublingual and will dissolve under the tongue. If swallowed whole, these tablets will not work as effectively and may result in withdrawal symptoms. Your doctor may prescribe more than one tablet a day; it is safe to take all the pills at once if you are able to do so. Do not alter the buprenorphine tablets or take them any other way than prescribed. An onset of withdrawal symptoms is likely should you abruptly stop taking this medication. If you have any questions or concerns while taking buprenorphine, discuss them with your nurse or doctor. Always follow your doctor's orders in regard to your treatment plan.

What Drug Interactions Should I Avoid When Taking Buprenorphine?

Your doctor needs a complete understanding of all medications you are currently taking since many drugs may react adversely in combination with buprenorphine. Be sure to tell your doctor if you are using a MAO inhibitor, any drugs that decrease your liver metabolism, erythromycin, local anesthetics or sedatives. Enzyme use should also be disclosed before taking buprenorphine. You should not take this drug with any other narcotics or alcohol. If you are using medication that induces drowsiness, speak to your doctor about its interaction with buprenorphine.

What are the Side Effects of Buprenorphine?

The following side effects are those most commonly experienced by people using buprenorphine. Should you experience any side effects not listed, tell you doctor immediately.

Drowsiness
Weakness
Constipation
Headache
Nausea
Vomiting

Although unlikely, buprenorphine may cause an allergic reaction. Slow, shallow breathing; mood changes or stomach pain could be a sign of a problem. Tell your doctor if any of these symptoms occur. Serious medical conditions such as dark urine, yellowing eyes or skin and vision changes need to be brought to your doctor's attention as soon as possible as they could signify jaundice. You should not experience severe opiate withdrawal symptoms as buprenorphine is designed to eliminate most of them. However, if you experience muscle stiffness or uncontrollable shaking, consult your doctor.

What Else Should I Know When Taking Buprenorphine?

It is possible to overdose on buprenorphine if you don't take it as prescribed. If you suspect an overdose, poison control (1-800-222-1222) or 911 will be able to assist you. You must take buprenorphine exactly as outlined in your treatment plan for it to be effective. It is important to let all your doctors know you are taking this prescription medication, especially in an emergency situation so that you may receive the best care for your medical condition. Some people may not be able to take buprenorphine for treatment based on their medical history. Some blood test or laboratory tests are recommended to ensure your physical progress and to reveal any side effects that may be otherwise escape unnoticed.

How Does Meditox Utilize Buprenorphine in Drug Addiction Treatment?

Buprenorphine is prescribed in two separate medications at Meditox, Subutex and Suboxone. Subutex is pure buprenorphine, and Suboxone combines buprenorphine with naloxone. As part of our drug addiction treatment, we provide our patients with a safe detox personalize to ensure minimal withdrawal symptoms. Our doctors are each qualified with DEA identification numbers and are federally certified to provide in-office prescriptions to give our clients. If you have any questions about a buprenorphine detox or buprenorphine treatment, please contact our Meditox calling center and speak to one of our intake counselors today.

If you feel that Meditox might be the right solution for you or your loved one, please call us for a toll-free and private consultation:

Additional Resources

Wikipedia: Buprenorphine
U.S. Food and Drug Administration: Subutex and Suboxone Information

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August 11, 2006

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